fIRST STRIKE

Innovative fomrula to support a healthy digestion from the stomach

Complete digestion of all macronutrients

The different enzymes that makeup Enzymax First Strike, will digest the fats, carbohydrates and proteins present in people´s daily diet.

The Role of Digestion in Health and Well-being

Human digestion is fundamental to nutrition, health, and well-being. Maintaining the balance of the digestive process is vital, as disruptions can lead to nutritional issues and health complications. Digestion’s primary purpose is to break down food into nutrients small enough to be absorbed into the bloodstream and delivered to cells for energy and repair.

The process involves mechanical and chemical actions across four main compartments of the gastrointestinal tract: the mouth, stomach, small intestine, and large intestine. Enzymes play a crucial role, breaking down carbohydrates, proteins, fats, and nucleic acids. These enzymes function in specific pH conditions in different parts of the digestive system. For example, salivary amylase works in the mouth at a neutral pH, while enzymes like pepsin operate in the acidic environment of the stomach.

The pancreas is essential for digestion, producing enzymes such as trypsin, lipase, and amylase. Disorders impairing pancreatic function can lead to malabsorption, diarrhea, and malnutrition. Treatments often involve exogenous enzyme supplements to aid nutrient breakdown and absorption.

  • Dyspepsia, or indigestion, includes upper gastrointestinal symptoms like abdominal discomfort, nausea, and early satiety. It is commonly triggered by diet, with foods like sausages, pizza, and soft drinks exacerbating symptoms. While dyspepsia can result from conditions like ulcers or gastric cancer, most cases are classified as functional dyspepsia, accounting for over 70% of dyspeptic cases. This condition arises from a combination of visceral hypersensitivity, gastric motor dysfunction, and psychological factors, significantly reducing patients’ quality of life.
 

Transient deficiencies in digestive enzymes are linked to functional dyspepsia. Oral enzyme supplements, such as animal-derived pancreatin, are frequently used to manage symptoms. To protect these enzymes from stomach acid, enteric-coated tablets are employed. However, these tablets may have drawbacks, including delayed stomach emptying and poor enzyme distribution.

Efficient Digestion with Advanced Enzyme Formulation

Optimized microbial enzymes for comprehensive digestion, safe and clinically proven to alleviate dyspepsia symptoms.
  • Efficiency. Contains microbial enzymes optimized for activity across a wide pH range, especially under acidic stomach conditions, ensuring effective digestion.
  • Advanced Formulation. Includes multiple enzymes (lipase, amylase, glucoamylase, and proteases) designed to comprehensively improve the digestion of fats, carbohydrates, and proteins from the stomach.
  • Safety. Recognized as safe (GRAS) by the FDA, with a long history of use without adverse effects in humans or animals.
  • Proven Clinical efficacy. Relieves symptoms of functional dyspepsia, including bloating, belching, heartburn, and loss of appetite, as demonstrated in clinical and post-marketing studies.

Enzymes for Efficient Digestion

Enzymes in Enzymax First Strike optimize digestion for better nutrient absorption.
  • Lipases are essential enzymes that break down dietary fats like triglycerides and phospholipids into glycerol and fatty acids, enabling absorption. Produced by plants, animals, and microorganisms, lipases are highly efficient, with >95% of dietary fats typically absorbed. The fungal lipases in Enzymax First Strike are optimized to function effectively in the acidic environment of the stomach.
  • Proteases digest dietary proteins into amino acids, which are vital for growth, repair, and bodily functions. Enzymax First Strike includes two fungal proteases, developed via microbial fermentation, with a wide pH range and optimal activity under acidic conditions.
  • Amylases are enzymes that break down starches, which form 40-50% of the Western diet, into glucose for absorption. Microbial-derived amylases, like those in Enzymax First Strike, are stable and active across a broad pH range, supporting digestion in stomach conditions.
  • Glucoamylases convert partially processed starch into glucose, aiding in carbohydrate digestion. Enzymax First Strike includes glucoamylase standardized for stability and activity across various pH levels, ensuring effective digestion and improved digestive health.

Clinical Studies

Proprietary Study on Hydrolytic Efficiency of Microbe-Derived Enzymes

  • Evaluate the hydrolytic activity of microbial enzymes under stomach conditions to assess their efficacy in food digestion.
  • Conclusion: The study demonstrated the effective disintegration of enzyme capsules under acidic stomach conditions. Microbial enzymes showed significant hydrolytic efficiency, digesting carbohydrates within 20 minutes and fats and proteins within 2 hours. These findings highlight the potential of microbe-derived enzymes to enhance digestion, reduce indigestion, and improve the quality of food absorption, ultimately supporting human nutrition.

Lipase Supplementation Before High-Fat Meals

  • Assess the effects of acid-resistant lipase on gastrointestinal symptoms, particularly fullness, after consuming a high-fat meal.
  • Conclusion: In a double-blind, placebo-controlled study with 16 healthy volunteers, lipase supplementation reduced the sensation of fullness compared to the placebo. This highlights its potential to improve comfort after high-fat meals.

Post-Marketing Surveillance Study on Microbial Enzymes for Dyspepsia

  • Evaluate the efficacy and tolerability of a multi-enzyme preparation in alleviating symptoms of functional dyspepsia.
  • Conclusion: Over a 14-day surveillance of 2,125 patients with functional dyspepsia, microbe-derived enzymes effectively reduced symptoms such as bloating, belching, heartburn, and abdominal discomfort, improving overall quality of life without adverse effects.

Clinical Trial on Microbial Enzymes for Functional Dyspepsia

  • Test the effectiveness of enzyme supplementation in improving symptoms of functional dyspepsia compared to a placebo.
  • Conclusion: In a trial of 40 patients, enzyme supplementation demonstrated significant symptom relief. The formula required lower doses than animal-based enzymes while maintaining efficacy.

How Does FIRST STRIKE Works?

Enzymax First Strike helps break down food into absorbable nutrients, preventing indigestion and discomfort.
The microbe derived enzymes of our Enzymax First Strike are carefully selected to be active at the pH conditions of the stomach. After entering the stomach, the capsule will disintegrate, allowing the digestive enzymes to break down the food into less complex and absorbable nutrients. This process will avoid indigestion and the sensation of fullness, as a proper and well-digested chyme, will be delivered to the small intestine.
Functional indigestion due to digestive enzyme deficiency or imbalance, such symptoms as dyspepsia, postprandial discomfort and epigastric fullness.
Take 1 or 2 capsules per meal. The maximum dose per day 4 capsules
It is recommended not to exceed the stated recommended daily dose. Food supplements should not replace a varied and balanced diet and a mode healthy life. Keep in a cool and dry place, below 25ºC and protected from sunlight and direct heat. Keep out of reach of children. Consult your doctor if you are on medication, pregnant, breastfeeding or suffer from food allergies. Do not use if you are allergic to any of the ingredients. According to the technical information available, Enzymax First Strike is well-tolerated with no significant side effects at the indicated doses. Consult your physician before using this product in case of pregnancy or breastfeeding.

About Aora Health

A Nutraceutical Research and Development Company

We create innovative, scientifically proven solutions with specific benefits designed to complement or substitute pharmaceuticals.

Our mission is to enhance people’s well-being through nutraceutical products with proven benefits and the backing of scientific research.